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Sunday, December 31, 2017

Introduction to Biochemistry - Quiz 3.8.5.3


Insulin inhibits gluconeogenesis and glycogenolysis in liver
Insulin is secreted when blood glucose is high


By triggering fusion of intracellular GLUT4 vesicles to the plasma membrane.


It promotes glucose transporter vesicle fusion in myocytes correct
It promotes glucose transporter vesicle fusion in adipocytes correct


FOXO1 is a transcription factor for gluconeogenesis genes in liver
PKB inhibits gluconeogenesis in liver


It is caused by poor cellular glucose uptake
Glucose in the urine is an early indicator of hyperglycemia
Hyperglycemia is defined by blood glucose over 126 mg/dL for fasting adults


Impaired tissue glucose uptake due to lack of insulin


VLDL secretion is increased
Ketone body production is increased

All other 3 options does not make sense because lack of insulin should lead to reduced energy storage and increased glucose production.

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