Introduction to Biochemistry - Quiz 3.8.2

The Fructose-1,6-Bisphosphate to Fructo-6-Phosphate step is reciprocally regulated by both allosteric and hormonal control.

The Pyruvate to Phosphoenolpyruvate step is reciprocally regulated by allosteric molecules.

The key regulation points are:

The carboxylase and dehydrogenase acting on pyruvate, and
The kinase and phosphatase acting on fructose-6-phosphate and fructo-1,6-bisphosphate, respectively.

They are the key point for regulation because the reaction and hard to reverse.

I cheated this one when I write this, the answer is PFK2/FBPase2

Here is my inference:

Glucagon indicates a low level of blood glucose (memonics - insulin, its 'enemy', signal the high level of blood glucose). With low level of blood glucose, we need to have more gluconeogenesis and less glycolysis.

Fructo-2,6-bisphosphate reduce the sensitivity of ATP to fructose-6-phosphate to fructo-1,6-bisphosphate step (I remembered this)

Fructo-2,6-bisphosphate thus promote glycolysis. In the case of low blood glucose, we do not want glycolysis, so we do not want fructose-2,6-bisphosphate.

Therefore Protein Kinase A phosphorylates and inactivate PFK2, it phosphorylates and activate FBPase2, both action is done to reduce the quantity of fructose-2,6-bisphosphate.

And then Wikipedia confirmed my interference is correct.