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Saturday, December 23, 2017

Introduction to Biochemistry - Quiz 3.7.3


AMP is at low abundance in cell, so a small decrease in [ATP] leads to large changes in [AMP].


Whatever added is an inhibitor, citrate make sense to inhibit glycolysis because that indicate high energy state. ATP also indicate a high energy state and that's why it also inhibit glycolysis.


It is an allosteric activator (I cheated - I forgot and Googled the result), and
It decreases the sensitivity of PFK-1 to ATP. (The make sense because we wanted to activate glycolysis)


A is Fructose
B is Fructose-1,6-bisphosphate
C is Fructose-6-phosphate
D is Fructose-2,6-bisphosphate

Therefore

C is the substrate for PFK-1 and PFK-2.
B is an allosteric regulator of PFK-1
D is the product of PFK-1

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