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Saturday, June 17, 2017

Introduction to Biochemistry - End of session 1 assessment


I failed this one personally, that is a really stupid mistake :(
I was tricked by the fact that we are asking the opposite question as we did in the first quiz.
Of course, Oxygen and Nitrogen is more abundant in living organism than Icon, Silicon and Calcium.



The molecule is symmetric, therefore the difference in electronegativity $ (\Delta EN) $ is 0. The carbon has three electron domain, therefore it is $ sp^2 $ hybridized and is trigonal planar.


This molecule is NOT chiral because we have two identical hydrogen bonded to it.


This molecule is chiral. To see that, the lower right carbon is $ sp^3 $ hybridized and is bonded to four different groups.


The only difference between the left and right and that the left hand side of the molecule is flipped. The number of types of atoms does not change, therefore the chemical formula is the same.

Looking at the carbon atom that is at the hinge of the flip. It is impossible for the molecule to change from one to the other without breaking a bond, therefore it is a configuration change, not a conformational change.



Use inorganic molecule for chemical energy - i.e. Chemo
Fix carbon dioxide for backbone - auto

This bacteria is a chemoautotroph.


H is the internal energy - the total amount of energy in the system.


$ \Delta G = \Delta H - T \Delta S = -10 -(-15) = 5 $ Kj/mol, therefore the reaction is non-spontaneous.


Again, $ \Delta G = \Delta H - T \Delta S $, but in this case we are having a positive number minus a positive number, we do not know if the output will be negative or not. Therefore the answer is "It depends on the temperature". The hotter, the more favorable it would be.


$ K_{eq} = 4 = \frac{[P_{eq}]}{[S_{eq}]} $ implies when [S] is 10 M, [P] should be 40 M, but we have only 1M of [P], so the forward reaction is spontaneous. 


$ \Delta G = \Delta H - T \Delta S = 100 - (273 + 27) \times 0.333 = 0.1 $

If the temperature increase, the $ \Delta G $ will decrease, and therefore the reaction will be spontaneous.

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